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Sildalist is a medication that combines two active ingredients: sildenafil and tadalafil. Both sildenafil and tadalafil are used to treat erectile dysfunction (ED) in men, but they work in slightly different ways. Sildenafil belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors, while tadalafil also belongs to this class but has a longer duration of action compared to sildenafil.