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Revatio is a medication that relaxes blood vessel muscles and increases blood flow to specific body areas. It is used to treat pulmonary arterial hypertension and improve exercise capacity in both men and women. It is not recommended to take Viagra while taking Revatio unless prescribed by a doctor. Revatio should not be taken with nitrate drugs for chest pain or heart problems, such as nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, or recreational drugs like "poppers." Taking Revatio with nitrates can cause a sudden and serious decrease in blood pressure.

Revatio should not be used if you are allergic to sildenafil or if you are taking other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas). Additionally, taking sildenafil with nitrates can cause a sudden and serious decrease in blood pressure.

To ensure the safety of Revatio, it is important to inform your doctor about any history of heart problems, blood circulation problems, retinitis pigmentosa, blindness, bleeding problems, stomach ulcers, pulmonary veno-occlusive disease (PVOD), liver or kidney disease, blood cell disorders, penis deformities, or health-related restrictions on sexual intercourse.

Sildenafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking sildenafil, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or pre-existing eye problems. It is unclear whether this medicine is the actual cause of vision loss.