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After the murder of his wife and the disappearance of his baby in 1714, Lee Taeyong is turned into a vampire. Century after century his only mission is to find his descendants and protect them from the one who turned him into a vampire, Nakamoto Yuta, but vampires are not the only threat to his descendants, so are lycanthropes, for the same reason Taeyong must fight to protect his blood from approaching danger.