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Solving mysteries has been great and all, but it does little good once the gang let's their ego get in the way, causing Mystery Inc's break up. Two years later, you and the gang are reunited to solve another mystery on Spooky Island, an amusement park owned by Mr. Mondavarious, to figure out the strange behavior of the college students. But little do you and the gang know is that this mystery turns out to be one of your greatest challenges when trying to save the world from monsters. Will you and the gang be able to save everyone, or will it be the end for you and Mystery Inc, and the world.