Powder can't remember her real name or who she was before she came to the Dollhouse. She doesn't even remember how she got there. In a seemingly-endless mansion of opulence and creatures lurking in shadows, Powder comes under the influence of the Monstress-a beautiful and eccentric woman who has created humanlike dolls to do her bidding and play out her fantasies. When Powder realizes her human body cannot withstand the supernatural forces of the Dollhouse, her only hope for escape is to build trust with both the dolls as well as the volatile Monstress herself. But one of the dolls develops feelings for Powder, and the jealous Monstress' cruelty knows no limits.