One

Mary Grimes was dying after the prison attack. She would have died, if Michonne hadn't saved her when everyone else, including her father, presumed she was dead.
Rick Grimes was lost after the prison attack. He had lost both of his daughters and his home, losing everything he wanted for his children.
Carl Grimes was broke. After the prison attack. He'd lost his sisters, his friends, all of his family. Losing his mother was horrific, but losing his little sisters was slowly killing him.

Then they found each other.

But that wasn't the first, or last, time they would face a hardship.

Mary Grimes was a fighter who claimed she wasn't scared of anything.